治疗帕金森病的脑深部电刺激手术中的图像引导:综述
Image guidance in deep brain stimulation surgery to treat Parkinson's disease: a review
AI总结:
本文综述了治疗帕金森病的图像引导脑深部电刺激手术的前沿技术,分析了图像引导对手术精准性、疗效和安全性的作用,并探讨了相关技术的优缺点与未来发展方向。
摘要:
脑深部电刺激(DBS)是一种可替代药物治疗帕金森病(PD)的有效疗法。除了器械、治疗方案和手术流程等因素外,手术的成功很大程度上取决于电极能否被精准放置在最佳治疗靶点内,同时避开可能引发手术并发症和不良神经效应的重要结构。尽管DBS的具体手术技术各有不同,但借助医学影像的介入引导已极大推动了该手术的发展、疗效提升和安全性保障。随着新型成像技术、计算方法和手术导航软件的快速发展,以及人们对该疾病和DBS作用机制的认识不断加深,现代图像引导有望进一步提升该手术治疗PD的能力与疗效。本文调研了用于PD治疗的图像引导DBS手术的前沿技术,讨论了其优缺点以及该领域的未来发展方向。
英文摘要:
Deep brain stimulation (DBS) is an effective therapy as an alternative to pharmaceutical treatments for Parkinson's disease (PD). Aside from factors such as instrumentation, treatment plans, and surgical protocols, the success of the procedure depends heavily on the accurate placement of the electrode within the optimal therapeutic targets while avoiding vital structures that can cause surgical complications and adverse neurologic effects. While specific surgical techniques for DBS can vary, interventional guidance with medical imaging has greatly contributed to the development, outcomes, and safety of the procedure. With rapid development in novel imaging techniques, computational methods, and surgical navigation software, as well as growing insights into the disease and mechanism of action of DBS, modern image guidance is expected to further enhance the capacity and efficacy of the procedure in treating PD. This article surveys the state-of-the-art techniques in image-guided DBS surgery to treat PD, and discuss their benefits and drawbacks, as well as future directions on the topic.
机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。