Creating a database of 21cm brightness temperature signals from the Epoch of Reionisation (EoR) for an array of reionisation histories is a complex and computationally expensive task, given the range of astrophysical processes involved and the possibly high-dimensional parameter space that is to be probed. We utilise a specific type of neural network, a Progressively Growing Generative Adversarial Network (PGGAN), to produce realistic tomography images of the 21cm brightness temperature during the EoR, covering a continuous three-dimensional parameter space that models varying X-ray emissivity, Lyman band emissivity, and ratio between hard and soft X-rays. The GPU-trained network generates new samples at a resolution of $\sim 3'$ in a second (on a laptop CPU), and the resulting global 21cm signal, power spectrum, and pixel distribution function agree well with those of the training data, taken from the 21SSD catalogue \citep{Semelin2017}. Finally, we showcase how a trained PGGAN can be leveraged for the converse task of inferring parameters from 21cm tomography samples via Approximate Bayesian Computation.
In this paper we introduce Curriculum GANs, a curriculum learning strategy for training Generative Adversarial Networks that increases the strength of the discriminator over the course of training, thereby making the learning task progressively more difficult for the generator. We demonstrate that this strategy is key to obtaining state-of-the-art results in image generation. We also show evidence that this strategy may be broadly applicable to improving GAN training in other data modalities.
We introduce a novel generative autoencoder network model that learns to encode and reconstruct images with high quality and resolution, and supports smooth random sampling from the latent space of the encoder. Generative adversarial networks (GANs) are known for their ability to simulate random high-quality images, but they cannot reconstruct existing images. Previous works have attempted to extend GANs to support such inference but, so far, have not delivered satisfactory high-quality results. Instead, we propose the Progressively Growing Generative Autoencoder (PIONEER) network which achiev…
GAN-Based Architecture for Low-dose Computed Tomography Imaging Denoising
College of Life Science and Technology, Huazhong University of Science and Technology（华中科技大学生命科学技术学院）；New York University Shanghai（上海纽约大学）；School of Life Sciences and Biotechnology, Shanghai Jiao Tong University（上海交通大学生命科学技术学院）
University of the Witwatersrand, Johannesburg（金山大学（约翰内斯堡））；Helen Joseph Hospital（海伦·约瑟夫医院）
Chest x-rays are a vital tool in the workup of many patients. Similar to most medical imaging modalities, they are profoundly multi-modal and are capable of visualising a variety of combinations of conditions. There is an ever pressing need for greater quantities of labelled data to develop new diagnostic tools, however this is in direct opposition to concerns regarding patient confidentiality which constrains access through permission requests and ethics approvals. Previous work has sought to address these concerns by creating class-specific GANs that synthesise images to augment training dat…
We present a framework for translating unlabeled images from one domain into analog images in another domain. We employ a progressively growing skip-connected encoder-generator structure and train it with a GAN loss for realistic output, a cycle consistency loss for maintaining same-domain translation identity, and a semantic consistency loss that encourages the network to keep the input semantic features in the output. We apply our framework on the task of translating face images, and show that it is capable of learning semantic mappings for face images with no supervised one-to-one image map…
Université Catholique de Louvain - ICTEAM（天主教鲁汶大学ICTEAM研究所）；Université Catholique de Louvain - IREC/MIRO（天主教鲁汶大学IREC/MIRO研究所）
With the advent of Deep Learning (DL) techniques, especially Generative Adversarial Networks (GANs), data augmentation and generation are quickly evolving domains that have raised much interest recently. However, the DL techniques are data demanding and since, medical data is not easily accessible, they suffer from data insufficiency. To deal with this limitation, different data augmentation techniques are used. Here, we propose a novel unsupervised data-driven approach for data augmentation that can generate 2D Computed Tomography (CT) images using a simple GAN. The generated CT images have g…
Linköping University（林雪平大学）；Center for Medical Image Science and Visualization, Linköping University（林雪平大学医学影像科学与可视化中心）；Sectra AB（Sectra公司）
Insufficient training data is a major bottleneck for most deep learning practices, not least in medical imaging where data is difficult to collect and publicly available datasets are scarce due to ethics and privacy. This work investigates the use of synthetic images, created by generative adversarial networks (GANs), as the only source of training data. We demonstrate that for this application, it is of great importance to make use of multiple GANs to improve the diversity of the generated data, i.e. to sufficiently cover the data distribution. While a single GAN can generate seemingly divers…
University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）
The objective optimization of medical imaging systems requires full characterization of all sources of randomness in the measured data, which includes the variability within the ensemble of objects to-be-imaged. This can be accomplished by establishing a stochastic object model (SOM) that describes the variability in the class of objects to-be-imaged. Generative adversarial networks (GANs) can be potentially useful to establish SOMs because they hold great promise to learn generative models that describe the variability within an ensemble of training data. However, because medical imaging syst…
We describe a new training methodology for generative adversarial networks. The key idea is to grow both the generator and discriminator progressively: starting from a low resolution, we add new layers that model increasingly fine details as training progresses. This both speeds the training up and greatly stabilizes it, allowing us to produce images of unprecedented quality, e.g., CelebA images at 1024^2. We also propose a simple way to increase the variation in generated images, and achieve a record inception score of 8.80 in unsupervised CIFAR10. Additionally, we describe several implementa…
Eindhoven University of Technology（埃因霍温理工大学）；Zhejiang University（浙江大学）；University of Texas at Austin（德克萨斯大学奥斯汀分校）；JD Explore Academy（京东探索研究院）
Generative adversarial networks (GANs) have received an upsurging interest since being proposed due to the high quality of the generated data. While achieving increasingly impressive results, the resource demands associated with the large model size hinders the usage of GANs in resource-limited scenarios. For inference, the existing model compression techniques can reduce the model complexity with comparable performance. However, the training efficiency of GANs has less been explored due to the fragile training process of GANs. In this paper, we, for the first time, explore the possibility of …
Washington University in St. Louis（圣路易斯华盛顿大学）；University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；Carle Foundation Hospital（卡尔基金会医院）
It has been advocated that medical imaging systems and reconstruction algorithms should be assessed and optimized by use of objective measures of image quality that quantify the performance of an observer at specific diagnostic tasks. One important source of variability that can significantly limit observer performance is variation in the objects to-be-imaged. This source of variability can be described by stochastic object models (SOMs). A SOM is a generative model that can be employed to establish an ensemble of to-be-imaged objects with prescribed statistical properties. In order to accurat…
University of Tübingen（图宾根大学）；Max Planck Institute for Intelligent Systems（马克斯·普朗克智能系统研究所）
Image-to-image translation plays a vital role in tackling various medical imaging tasks such as attenuation correction, motion correction, undersampled reconstruction, and denoising. Generative adversarial networks have been shown to achieve the state-of-the-art in generating high fidelity images for these tasks. However, the state-of-the-art GAN-based frameworks do not estimate the uncertainty in the predictions made by the network that is essential for making informed medical decisions and subsequent revision by medical experts and has recently been shown to improve the performance and inter…
We report, to our knowledge, the first end-to-end application of Generative Adversarial Networks (GANs) towards the synthesis of Optical Coherence Tomography (OCT) images of the retina. Generative models have gained recent attention for the increasingly realistic images they can synthesize, given a sampling of a data type. In this paper, we apply GANs to a sampling distribution of OCTs of the retina. We observe the synthesis of realistic OCT images depicting recognizable pathology such as macular holes, choroidal neovascular membranes, myopic degeneration, cystoid macular edema, and central se…
Recent generative adversarial networks (GANs) are able to generate impressive photo-realistic images. However, controllable generation with GANs remains a challenging research problem. Achieving controllable generation requires semantically interpretable and disentangled factors of variation. It is challenging to achieve this goal using simple fixed distributions such as Gaussian distribution. Instead, we propose an unsupervised framework to learn a distribution of latent codes that control the generator through self-training. Self-training provides an iterative feedback in the GAN training, f…
Columbia University（哥伦比亚大学）；Stanford University（斯坦福大学）
Generative adversarial networks, which can generate metasurfaces based on a training set of high performance device layouts, have the potential to significantly reduce the computational cost of the metasurface design process. However, basic GAN architectures are unable to fully capture the detailed features of topologically complex metasurfaces, and generated devices therefore require additional computationally-expensive design refinement. In this Letter, we show that GANs can better learn spatially fine features from high-resolution training data by progressively growing its network architect…
University of Toronto（多伦多大学）；Vector Institute（向量研究所）；Nvidia（英伟达）；Mila（米拉研究所）；Google Brain（谷歌大脑）
Convolutional Neural Networks (CNNs) have shown impressive performance in computer vision tasks such as image classification, detection, and segmentation. Moreover, recent work in Generative Adversarial Networks (GANs) has highlighted the importance of learning by progressively increasing the difficulty of a learning task [26]. When learning a network from scratch, the information propagated within the network during the earlier stages of training can contain distortion artifacts due to noise which can be detrimental to training. In this paper, we propose an elegant curriculum based scheme tha…
NVIDIA Corporation（英伟达公司）；Seoul National University（首尔大学）
Positron Emission Tomography (PET) is now regarded as the gold standard for the diagnosis of Alzheimer's Disease (AD). However, PET imaging can be prohibitive in terms of cost and planning, and is also among the imaging techniques with the highest dosage of radiation. Magnetic Resonance Imaging (MRI), in contrast, is more widely available and provides more flexibility when setting the desired image resolution. Unfortunately, the diagnosis of AD using MRI is difficult due to the very subtle physiological differences between healthy and AD subjects visible on MRI. As a result, many attempts have…
From Characterization To Construction: Generative Quantum Circuit Synthesis from Gate Set Tomography Data
Quantum and Computer Engineering, Delft University of Technology, The Netherlands（量子与计算机工程系，代尔夫特理工大学，荷兰）；QuTech, Delft University of Technology, The Netherlands（QuTech，代尔夫特理工大学，荷兰）；Kavli Institute of Nanoscience Delft, Delft University of Technology, The Netherlands（代尔夫特纳米科学研究所Kavli，代尔夫特理工大学，荷兰）
While energy-based models (EBMs) exhibit a number of desirable properties, training and sampling on high-dimensional datasets remains challenging. Inspired by recent progress on diffusion probabilistic models, we present a diffusion recovery likelihood method to tractably learn and sample from a sequence of EBMs trained on increasingly noisy versions of a dataset. Each EBM is trained with recovery likelihood, which maximizes the conditional probability of the data at a certain noise level given their noisy versions at a higher noise level. Optimizing recovery likelihood is more tractable than …
German Cancer Research Center (DKFZ)（德国癌症研究中心）；Heidelberg University（海德堡大学）；Helmholtz Information and Data Science School for Health（亥姆霍兹健康信息与数据科学学院）；Cancer Research UK Cambridge Institute, University of Cambridge（剑桥大学英国癌症研究中心剑桥研究所）
Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were hampered by the absence of labeled reference data. While this bottleneck has been tackled by simulating training data, the domain gap between real and simulated images remains an unsolved challenge. We propose a novel approach to PAT image synthesis that involves subdividing the challenge of generating plausible simulations into two disjoint problems: (1) Pro…
University of Chinese Academy of Sciences（中国科学院大学）；JD AI Research（京东人工智能研究院）
Single image generation (SIG), described as generating diverse samples that have similar visual content with the given single image, is first introduced by SinGAN which builds a pyramid of GANs to progressively learn the internal patch distribution of the single image. It also shows great potentials in a wide range of image manipulation tasks. However, the paradigm of SinGAN has limitations in terms of generation quality and training time. Firstly, due to the lack of high-level information, SinGAN cannot handle the object images well as it does on the scene and texture images. Secondly, the se…
The explosive rise of the use of Computer tomography (CT) imaging in medical practice has heightened public concern over the patient's associated radiation dose. However, reducing the radiation dose leads to increased noise and artifacts, which adversely degrades the scan's interpretability. Consequently, an advanced image reconstruction algorithm to improve the diagnostic performance of low dose ct arose as the primary concern among the researchers, which is challenging due to the ill-posedness of the problem. In recent times, the deep learning-based technique has emerged as a dominant method…
The University of Texas MD Anderson Cancer Center（德克萨斯大学MD安德森癌症中心）；Rice University（莱斯大学）；University of California San Diego（加州大学圣地亚哥分校）
Although generative adversarial networks (GANs) have shown promise in medical imaging, they have four main limitations that impeded their utility: computational cost, data requirements, reliable evaluation measures, and training complexity. Our work investigates each of these obstacles in a novel application of StyleGAN2-ADA to high-resolution medical imaging datasets. Our dataset is comprised of liver-containing axial slices from non-contrast and contrast-enhanced computed tomography (CT) scans. Additionally, we utilized four public datasets composed of various imaging modalities. We trained …
