A mirrored bilayer structure incorporating layers of Graphene and MoS2 is proposed here for Surface Plasmon Resonance (SPR) biosensing and its performance is evaluated numerically. Starting from the basic configuration, the structure with graphene and MoS2 layers is gradually developed for enhanced performance. Reflectance is the main considered parameter for performance analysis. A theoretical framework based on Fresnel's equations is presented and by measuring reflectance versus angle of incidence, sensitivity is calculated from the displacement of SPR angle using finite-difference time-domain (FDTD) technique. Our numerical analysis shows that using the proposed approach, about 4.2 times enhanced sensitivity can be achieved compared to the basic Kretschmann configuration. Notably, the structure provides an enhancement for both angular and wavelength interrogations. Furthermore, simulations have been repeated for various ligate-ligand pairs and consistent enhancement has been observed which proves the robustness of the structure. So, the proposed sensor architecture clearly provides pronounced improvement in sensitivity which can be significant in various practical applications.
A surface plasmon resonance imaging biosensor based on $\text{MoS}_2$ deposited on Aluminium substrate is designed for high imaging sensitivity and detection accuracy. The proposed biosensor exhibits better performance than graphene-based biosensor in the near-infrared regime. A high imaging sensitivity of more than 970 $\text{RIU}^{-1}$ is obtained at the wavelength of 1540 nm. The effect of aluminium thickness, number of $\text{MoS}_2$ layers and the refractive index of sensing layer are investigated to obtain an optimized design for high sensor performance. In addition, the sensor performan…
Two-dimensional transition metal dichalcogenides (TMDCs), as promising alternative plasmonics supporting materials to graphene, exhibit potential applications in sensing. Here, we propose an ultrasensitive, accurate long-range surface plasmon resonance (LRSPR) imaging biosensor with two-dimensional TMDC layers, which shows higher detection accuracy than that of conventional SPR biosensor. It is found that the imaging sensitivity of the proposed LRSPR biosensor can be enhanced by the integration of TMDC layers, which is different from the previous graphene-based LRSPR or SPR imaging sensor, who…
We analyze a whispering gallery mode biosensor with a metallic nanorod bound to its surface. It is found that a localized surface plasmon resonance in the nanorod can reduce the optical mode volume of the resonator by as much as four orders of magnitude via a local enhancement of the electric field, thus improving the detection sensitivity. Optical frequency shifts as large as 15 MHz are predicted for typical proteins and, for typical experimental parameters, the biosensor is predicted to be limited by laser frequency noise, leading to a minimum detectable polarizability on the order of 10 cub…
Surface plasmon polaritons (SPPs) are optical waves that propagate along a metal surface. They exhibit properties such as sub-wavelength localization and field enhancement which make them attractive for surface sensing, as commonly encountered in surface plasmon biosensors - the most widespread of all optical biosensors. Electrochemistry also occurs on metal surfaces, and electrochemical approaches are widely used to implement biosensors - electrochemical biosensors are the most prevalent biosensors in use. Given that metal surfaces are inherent to both techniques, it is natural to combine the…
One of the most important processes in the fight against current and future pandemics is the rapid diagnosis and initiation of treatment of viruses in humans. In these times, the development of high-sensitivity tests and diagnostic kits is an important research area. Plasmonic platforms, which control light in subwavelength volumes, have opened up exciting prospects for biosensing applications. Their significant sensitivity and selectivity allow for the non-invasive and rapid detection of viruses. In particular, plasmonic-assisted virus detection platforms can be achieved by various approaches…
Surface Plasmon Resonance (SPR) offers a powerful tool for label-free and non-invasive characterization of biomolecular interactions. To date, several experimental configurations, based on two fundamental physical phenomena, e.g., attenuated total reflection and diffraction, have been developed to measure the SPR signal generated due to the resonant interactions between incident light and plasma waves on the metal surface. These configurations are divided into three categories: grating-based, prism-based, and waveguide-based coupling. Among such techniques, one of the prism-based SPR coupling …
Biosensors exploiting long-range surface plasmon polariton (LRSPP) waveguides comprised of Au stripes embedded in Cytop with integrated and encapsulated microfluidic channels are fabricated and demonstrated. A fabrication approach was devised where the lower cladding and recessed Au stripes are fabricated on a Si substrate, and the upper cladding and microfluidic channels are fabricated on a glass substrate, followed by wafer bonding to assemble the wafers into complete structures. The bond is centered over the full length of the optical path, yet no evidence of optical scattering or excess lo…
We report Gold/Silica biochips for low cost biosensor devices. Firstly, the study of biochemical interactions on silica by means of Surface Plasmon Resonance (SPR) is presented. Secondly, Gold/Silica biochips are employed to reduce the strong quenching that occurs when a fluorophore is close to the gold surface. Furthermore, the control of the Silica-like thickness allows optimizing the distance between the metallic surface and the fluorophore in order to enhance the fluorescent signal. These results represent the first steps towards highly sensitive, specific and low cost biosensors based, fo…
Surface Plasmon Resonance (SPR) is an important bio-sensing technique for real-time label-free detection. However, it is pivotal to optimize various parameters of the sensor configuration for efficient and highly sensitive sensing. To that effect, we focus on optimizing two different SPR structures -- the basic Kretschmann configuration and narrow groove grating. Our analysis aims to detect two different types of lipids known as phospholipid and eggyolk, which are used as analyte (sensing layer) and two different types of proteins namely tryptophan and bovine serum albumin (BSA) are used as li…
We present a numerical study on a 2D array of plasmonic structures covered by a subwavelength film. We explain the origin of surface lattice resonances (SLRs) using coupled dipole approximation and show that the diffraction-assisted plasmonic resonances and formation of bound states in the continuum (BICs) can be controlled by altering the optical environment. Our study shows that when the refractive index contrast is small ( $Δ$n < -0.1), the SLR cannot be excited, while a significant contrast ($Δ$n > 0.3) not only sustains plasmonic-induced resonances but also forms both symmetry-protected a…
Surface plasmon polaritons (SPPs) are traditionally excited by plane waves within the Rayleigh range of a focused transverse magnetic (TM) Gaussian beam. Here, we investigate and confirm the coupling between SPPs and two-dimensional Gaussian and Bessel-Gauss wave packets, as well as one-dimensional light sheets and space-time wave packets. We encode the incoming wavefronts with spatially varying states of polarization then couple the respective TM components of radial and azimuthal vector beam profiles to confirm SPP polarization-correlation and spatial-mode selectivity. Our results do not req…
Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique electro-optical properties of graphene to demonstrate a high-sensitivity tunable plasmonic biosensor for chemically-specific label-free detection of protein monolayers. The plasmon resonance of nanostructured graphene is dynamically tuned to selectively probe the protein at different frequencies and extract its complex refractive index. Additionally, the extreme s…
A scheme for a surface plasmon resonance system under conditions of electromagnetically induced transparency (EIT) is proposed. The system is composed of three layers: a prism, a thin metal film, and a hybrid dielectric consisting of EIT atoms and a background substance. A probe and a coupling laser beam are input. Corresponding analytical formulas are derived for the cases when one or both of the laser beams excite surface plasmon polaritons at the metal/dielectric interface. Under resonance conditions, an extremely sharp dip appears in the reflectivity-frequency spectrum of the probe field, …
This article proposes a novel analytical model for the anisotropic multi-layer structures containing magnetically biased graphene sheets. The multi-layer structure is composed of various magnetic materials. An external magnetic field is applied, normal to the structure surface. Each graphene sheet, with an anisotropic conductivity tensor, has been sandwiched between two adjacent magnetic materials. Our model is used to find the dispersion relation of the structure. Now, obtaining plasmonic features of the structure, such as the effective index and propagation loss is straightforward. Four exem…
