相场胶原纤维：耦合手性和密度调制
Phase-field collagen fibrils: Coupling chirality and density modulations
摘要：
为了描述胶原纤维的纵向密度调制（D带）与分子取向的径向扭曲场（双扭曲）之间的相互作用，我们将相场晶体（PFC）与液晶自由能耦合，得到平衡胶原纤维结构的混合模型。我们数值计算所产生的轴向和径向结构。我们发现两个不同的纤维相，“L”和“C”，与共存线，结束在一个伊辛样的临界点。我们建议，这些阶段之间的共存可以解释双峰分布的原纤维半径已被广泛报道肌腱组织内。拉伸应变施加到我们的模型原纤拉直的平均原纤扭曲和D-band调制。我们的PFC方法应直接适用于其他经神经调节的手性纤维，如纤维蛋白和中间纤维。
英文摘要：
To describe the interaction between longitudinal density modulations along collagen fibrils (the D-band) with the radial twist-field of molecular orientation (double-twist), we couple phase-field-crystal (PFC) with liquid-crystalline free-energies to obtain a hybrid model of equilibrium collagen fibril structure. We numerically compute the resulting axial and radial structure. We find two distinct fibrillar phases, `L' and `C', with a coexistence line that ends in an Ising-like critical point. We propose that coexistence between these phases can explain the bimodal distribution of fibril radii that has been widely reported within tendon tissues. Tensile strain applied to our model fibrils straightens the average fibrillar twist and flattens the D-band modulation. Our PFC approach should apply directly to other longitudinally-modulated chiral filaments, such as fibrin and intermediate filaments.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
