The basic goal of threshold group testing is to identify up to $d$ defective items among a population of $n$ items, where $d$ is usually much smaller than $n$. The outcome of a test on a subset of items is positive if the subset has at least $u$ defective items, negative if it has up to $\ell$ defective items, where $0\leq\ell<u$, and arbitrary otherwise. This is called threshold group testing. The parameter $g=u-\ell-1$ is called \textit{the gap}. In this paper, we focus on the case $g>0$, i.e., threshold group testing with a gap. Note that the results presented here are also applicable to the case $g = 0$; however, the results are not as efficient as those in related work. Currently, a few reported studies have investigated test designs and decoding algorithms for identifying defective items. Most of the previous studies have not been feasible because there are numerous constraints on their problem settings or the decoding complexities of their proposed schemes are relatively large. Therefore, it is compulsory to reduce the number of tests as well as the decoding complexity, i.e., the time for identifying the defective items, for achieving practical schemes.
The work presented here makes five contributions. The first is a more accurate theorem for a non-adaptive algorithm for threshold group testing proposed by Chen and Fu. The second is an improvement in the construction of disjunct matrices, which are the main tools for tackling (threshold) group testing and other tasks such as constructing cover-free families or learning hidden graphs. The third and fourth contributions are a reduced exact upper bound on the number of tests and a reduced asymptotic bound on the decoding time for identifying defective items in a noisy setting on test outcomes. The fifth contribution is a simulation on the number of tests of the resulting improvements for previous work and the proposed theorems.
We consider adaptive group testing in the linear regime, where the number of defective items scales linearly with the number of items. We analyse an algorithm based on generalized binary splitting. Provided fewer than half the items are defective, we achieve rates of over 0.9 bits per test for combinatorial zero-error testing, and over 0.95 bits per test for probabilistic small-error testing.
In the group testing problem we aim to identify a small number of infected individuals within a large population. We avail ourselves to a procedure that can test a group of multiple individuals, with the test result coming out positive iff at least one individual in the group is infected. With all tests conducted in parallel, what is the least number of tests required to identify the status of all individuals? In a recent test design [Aldridge et al.\ 2016] the individuals are assigned to test groups randomly, with every individual joining an equal number of groups. We pinpoint the sharp thres…
The group testing problem is concerned with identifying a small number $k \sim n^θ$ for $θ\in (0,1)$ of infected individuals in a large population of size $n$. At our disposal is a testing procedure that allows us to test groups of individuals. This paper considers two-stage designs where the test results of the first stage can inform the design of the second stage. We are interested in the minimum number of tests to recover the set of infected individuals w.h.p. Equipped with a novel algorithm for one-stage group testing from [Coja-Oghlan, Gebhard, Hahn-Klimroth \& Loick 2019], we propose a p…
We explore the problem of deriving a posteriori probabilities of being defective for the members of a population in the non-adaptive group testing framework. Both noiseless and noisy testing models are addressed. The technique, which relies of a trellis representation of the test constraints, can be applied efficiently to moderate-size populations. The complexity of the approach is discussed and numerical results on the false positive probability vs. false negative probability trade-off are presented.
The group testing problem consists of determining a small set of defective items from a larger set of items based on a number of possibly-noisy tests, and has numerous practical applications. One of the defining features of group testing is whether the tests are adaptive (i.e., a given test can be chosen based on all previous outcomes) or non-adaptive (i.e., all tests must be chosen in advance). In this paper, building on the success of binary splitting techniques in noiseless group testing (Hwang, 1972), we introduce noisy group testing algorithms that apply noisy binary search as a subroutin…
In this paper, we consider the group testing problem with adaptive test designs and noisy outcomes. We propose a computationally efficient four-stage procedure with components including random binning, identification of bins containing defective items, 1-sparse recovery via channel codes, and a "clean-up" step to correct any errors from the earlier stages. We prove that the asymptotic required number of tests comes very close to the best known information-theoretic achievability bound (which is based on computationally intractable decoding), and approaches a capacity-based converse bound in th…
In this paper, we consider the problem of noiseless non-adaptive group testing under the for-each recovery guarantee, also known as probabilistic group testing. In the case of $n$ items and $k$ defectives, we provide an algorithm attaining high-probability recovery with $O(k \log n)$ scaling in both the number of tests and runtime, improving on the best known $O(k^2 \log k \cdot \log n)$ runtime previously available for any algorithm that only uses $O(k \log n)$ tests. Our algorithm bears resemblance to Hwang's adaptive generalized binary splitting algorithm (Hwang, 1972); we recursively work …
We propose two-stage adaptive pooling schemes, 2-STAP and 2-STAMP, for detecting COVID-19 using real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) test kits. Similar to the Tapestry scheme of Ghosh et al., the proposed schemes leverage soft information from the RT-qPCR process about the total viral load in the pool. This is in contrast to conventional group testing schemes where the measurements are Boolean. The proposed schemes provide higher testing throughput than the popularly used Dorfman's scheme. They also provide higher testing throughput, sensitivity and …
Among the challenges that the COVID-19 pandemic outbreak revealed is the problem to reduce the number of tests required for identifying the virus carriers in order to contain the viral spread while preserving the tests reliability. To cope with this issue, a prevalence testing paradigm based on group testing and compressive sensing approach or GTCS was examined. In these settings, a non-adaptive group testing algorithm is designed to rule out sure-negative samples. Then, on the reduced problem, a compressive sensing algorithm is applied to decode the positives without requiring any further tes…
We consider sequential hypothesis testing between two quantum states using adaptive and non-adaptive strategies. In this setting, samples of an unknown state are requested sequentially and a decision to either continue or to accept one of the two hypotheses is made after each test. Under the constraint that the number of samples is bounded, either in expectation or with high probability, we exhibit adaptive strategies that minimize both types of misidentification errors. Namely, we show that these errors decrease exponentially (in the stopping time) with decay rates given by the measured relat…
