绘制细菌的生活方式
Mapping the bacterial ways of life
摘要：
细菌基因组可用性的增加定义了对合成的需求：从单个分类群中提取，以查看跨系统的细菌生活方式的更大模式。生态学中这种综合的一个关键概念是生态位，即使一个种群能够持久存在并确定其对环境影响的一系列能力。可能的生态位的集合形成了生态位空间，这是一个概念空间，描绘了系统中持久性的可能方式。在这里，我们使用流形学习来映射代表数千种细菌属的代谢网络的空间。结果显示，代谢生态位空间具有复杂的分支几何形状，其分支构成了跨越不同栖息地和宿主的主要策略。我们进一步证明，社区从类似的生态系统类型映射到这个新的功能坐标系的特征区域，允许生态描述微生物组的大规模代谢作用，可以填补。
英文摘要：
The rise in the availability of bacterial genomes defines a need for synthesis: abstracting from individual taxa, to see larger patterns of bacterial lifestyles across systems. A key concept for such synthesis in ecology is the niche, the set of capabilities that enables a population's persistence and defines its impact on the environment. The set of possible niches forms the niche space, a conceptual space delineating ways in which persistence in a system is possible. Here we use manifold learning to map the space of metabolic networks representing thousands of bacterial genera. The results reveal a metabolic niche space with a complex branching geometry, whose branches constitute major strategies spanning life in different habitats and hosts. We further demonstrate that communities from similar ecosystem types map to characteristic regions of this new functional coordinate system, permitting ecological descriptions of microbiomes in terms of large scale metabolic roles that may be filled.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
