入侵与遗传损失的环境失调调控
Environmental Disorder Regulation of Invasion and Genetic Loss
摘要：
许多物理和自然系统，包括物种的种群，在生境中进化的空间随机变化的个人的运动。我们在这里研究这些波动对入侵和遗传损失的影响。得到了侵入锋的\textit{position}和\textit{border}的朗之万方程。一个引人注目的结果是，小/大波动的扩散抑制/加剧遗传损失。我们的研究结果揭示了环境波动作为遗传丢失的调节因素的潜在作用，并为在人类进化的最后阶段和肿瘤突变景观中观察到的遗传漂变强度的区域差异提供了简单的解释。
英文摘要：
Many physical and natural systems, including the population of species, evolve in habitats with spatial stochastic variations of the individuals' motility. We study here the effect of those fluctuations on invasion and genetic loss. A Langevin equation for the \textit{position} and \textit{border} of the invasion front is obtained. A striking result is that small/large fluctuations of diffusivity suppress/intensify genetic loss. Our findings reveal the potential role of environmental fluctuations as a regulating factor for genetic loss and provide a simple explanation for the regional differences in the intensity of genetic drift observed during the final stages of human evolution and in tumor mutational landscapes.
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