工作记忆过程中的大脑状态稳定性可以用网络控制理论来解释，多巴胺D1/D2受体功能可以调节大脑状态稳定性，精神分裂症患者的大脑状态稳定性降低
Brain state stability during working memory is explained by network control theory, modulated by dopamine D1/D2 receptor function, and diminished in schizophrenia
摘要：
动态的大脑状态转换对于灵活的工作记忆是至关重要的，但其网络机制还不完全清楚。在这里，我们表明，工作记忆需要大脑活动状态之间的切换。状态的稳定性与多巴胺D1受体基因表达有关，而状态转换受D2受体表达和药理学调节的影响。精神分裂症患者表现出改变的网络控制特性，包括更多样化的能量景观和工作记忆表征的稳定性下降。
英文摘要：
Dynamical brain state transitions are critical for flexible working memory but the network mechanisms are incompletely understood. Here, we show that working memory entails brainwide switching between activity states. The stability of states relates to dopamine D1 receptor gene expression while state transitions are influenced by D2 receptor expression and pharmacological modulation. Schizophrenia patients show altered network control properties, including a more diverse energy landscape and decreased stability of working memory representations.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
