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arXiv 1902.03362physics.med-phcs.LGstat.ML

Sinogram interpolation for sparse-view micro-CT with deep learning neural network

Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences(弗吉尼亚理工-维克森林大学生物医学工程与科学学院);Virginia Polytechnic Institute and State University(弗吉尼亚理工学院暨州立大学)

Xu Dong, Swapnil Vekhande, Guohua Cao

英文摘要:

In sparse-view Computed Tomography (CT), only a small number of projection images are taken around the object, and sinogram interpolation method has a significant impact on final image quality. When the amount of sparsity (the amount of missing views in sinogram data) is not high, conventional interpolation methods have yielded good results. When the amount of sparsity is high, more advanced sinogram interpolation methods are needed. Recently, several deep learning (DL) based sinogram interpolation methods have been proposed. However, those DL-based methods have mostly tested so far on computer simulated sinogram data rather experimentally acquired sinogram data. In this study, we developed a sinogram interpolation method for sparse-view micro-CT based on the combination of U-Net and residual learning. We applied the method to sinogram data obtained from sparse-view micro-CT experiments, where the sparsity reached 90%. The interpolated sinogram by the DL neural network was fed to FBP algorithm for reconstruction. The result shows that both RMSE and SSIM of CT image are greatly improved. The experimental results demonstrate that this sinogram interpolation method produce significantly better results over standard linear interpolation methods when the sinogram data are extremely sparse.

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