染色质构型异常与肿瘤发生的再思考
Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis
摘要：
30多年前，我们发表了一篇题为《异常染色质构型与肿瘤发生》的论文，提出了第一个将肿瘤发生与异常三维（3D）基因组结构联系起来的假说。近年来，许多研究表明，基因组的三维结构在肿瘤发生中起着重要作用，这有力地支持了我们的假设。在本文中，进一步思考我们的假设。
英文摘要：
More than 30 years ago, we published a paper entitled as abnormal chromatin configuration and oncogenesis, which proposed the first hypothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis is presented.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
