arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 1901.04094q-bio.NC
收藏

异质性尖峰神经元群体编码的动态刺激的最佳解码-一种封闭形式近似

Optimal decoding of dynamic stimuli encoded by heterogeneous populations of spiking neurons - a closed form approximation

Yuval Harel, Ron Meir, Manfred Opper

摘要:

神经解码可以被公式化为基于点过程观测的动态状态估计(滤波),这是一个通常难以处理的问题。数值采样技术对于真实神经数据的解码通常是实用的。然而,它们作为建模和理解感觉神经系统的理论工具不太有用,因为它们导致对最佳编码和解码策略的概念性见解有限。我们认为感觉神经元群体的特点是分布在神经元参数。我们开发了一个易于分析的贝叶斯近似最佳过滤的观察尖峰活动的基础上,极大地方便了分析的最佳编码的情况下偏离统一编码的共同假设。连续分布被用来近似具有很少参数的大群体,导致滤波器的复杂性不随群体大小而增长,并且允许优化群体参数而不是个体调谐函数。与粒子滤波的数值比较证明了近似的质量。的分析框架导致的见解,这是很难获得的数值算法,并与生物学观察的感觉细胞的首选刺激的分布是一致的。

英文摘要:

Neural decoding may be formulated as dynamic state estimation (filtering) based on point process observations, a generally intractable problem. Numerical sampling techniques are often practically useful for the decoding of real neural data. However, they are less useful as theoretical tools for modeling and understanding sensory neural systems, since they lead to limited conceptual insight about optimal encoding and decoding strategies. We consider sensory neural populations characterized by a distribution over neuron parameters. We develop an analytically tractable Bayesian approximation to optimal filtering based on the observation of spiking activity, that greatly facilitates the analysis of optimal encoding in situations deviating from common assumptions of uniform coding. Continuous distributions are used to approximate large populations with few parameters, resulting in a filter whose complexity does not grow with the population size, and allowing optimization of population parameters rather than individual tuning functions. Numerical comparison with particle filtering demonstrates the quality of the approximation. The analytic framework leads to insights which are difficult to obtain from numerical algorithms, and is consistent with biological observations about the distribution of sensory cells' preferred stimuli.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑