随机混合图与F-统计量的一般理论
General theory for stochastic admixture graphs and F-statistics
摘要:
我们提供了一个通用的数学框架的基础上的理论图模型来研究混合图。混合图用于描述过去和现在的人口之间的祖先关系,允许人口合并和迁移事件,通过基因流。我们给出了混合图的各种数学性质,特别关注所谓的$F$ -统计特性。研究了Wright-Fisher模型,导出了杂合性丢失的一般表达式。
英文摘要:
We provide a general mathematical framework based on the theory of graphical models to study admixture graphs. Admixture graphs are used to describe the ancestral relationships between past and present populations, allowing for population merges and migration events, by means of gene flow. We give various mathematical properties of admixture graphs with particular focus on properties of the so-called $F$-statistics. Also the Wright-Fisher model is studied and a general expression for the loss of heterozygosity is derived.
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