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arXiv 1806.07201cs.CV
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任务驱动的无监督领域自适应生成模型在X射线图像分割中的应用

Task Driven Generative Modeling for Unsupervised Domain Adaptation: Application to X-ray Image Segmentation

Case Western Reserve University(凯斯西储大学);Medical Imaging Technologies, Siemens Healthineers Technology Center(西门子医疗技术中心医学影像技术部)

Yue Zhang, Shun Miao, Tommaso Mansi, Rui Liao

摘要:

X射线图像中的解剖对象的自动解析对于许多临床应用是至关重要的,特别是对于图像引导的发明和工作流程自动化。现有的深度网络模型需要大量的标记数据。然而,由于解剖结构的大量重叠和复杂的纹理模式,在X射线图像中获得准确的逐像素标记在很大程度上依赖于熟练的临床医生。另一方面,3D CT扫描中的器官保留了更清晰的结构和更清晰的边界,因此可以很容易地描绘。在本文中,我们提出了一种新的模型框架,用于学习自动X射线图像解析标记的CT扫描。具体而言,首先在从3D CT体积绘制的X射线样数字重建放射照片(DRR)上训练用于多器官分割的密集图像到图像网络(DI 2 I)。然后,我们介绍了一个任务驱动的生成对抗网络(TD-GAN)的架构,以实现同步的风格传输和解析看不见的真实X射线图像。TD-GAN包括一个修改的cycle-GAN子结构,用于DRR和X射线图像之间的像素到像素转换,以及一个利用预训练的DI 2 I来执行分割一致性的附加模块。TD-GAN框架是通用的,可以很容易地适应其他学习任务。在数值实验中,我们验证了所提出的模型上的815 DRR和153地形。虽然没有任何自适应的香草DI 2 I在分割拓扑图时完全失败,但所提出的模型不需要任何拓扑图标签,并且能够提供85%的有希望的平均骰子,从而实现与监督训练相同的准确度(88%)。

英文摘要:

Automatic parsing of anatomical objects in X-ray images is critical to many clinical applications in particular towards image-guided invention and workflow automation. Existing deep network models require a large amount of labeled data. However, obtaining accurate pixel-wise labeling in X-ray images relies heavily on skilled clinicians due to the large overlaps of anatomy and the complex texture patterns. On the other hand, organs in 3D CT scans preserve clearer structures as well as sharper boundaries and thus can be easily delineated. In this paper, we propose a novel model framework for learning automatic X-ray image parsing from labeled CT scans. Specifically, a Dense Image-to-Image network (DI2I) for multi-organ segmentation is first trained on X-ray like Digitally Reconstructed Radiographs (DRRs) rendered from 3D CT volumes. Then we introduce a Task Driven Generative Adversarial Network (TD-GAN) architecture to achieve simultaneous style transfer and parsing for unseen real X-ray images. TD-GAN consists of a modified cycle-GAN substructure for pixel-to-pixel translation between DRRs and X-ray images and an added module leveraging the pre-trained DI2I to enforce segmentation consistency. The TD-GAN framework is general and can be easily adapted to other learning tasks. In the numerical experiments, we validate the proposed model on 815 DRRs and 153 topograms. While the vanilla DI2I without any adaptation fails completely on segmenting the topograms, the proposed model does not require any topogram labels and is able to provide a promising average dice of 85% which achieves the same level accuracy of supervised training (88%).

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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