记忆效应和Lévy Walk动力学在细胞内货物运输中的作用
Memory effects and Lévy walk dynamics in intracellular transport of cargoes
摘要：
我们证明了在细胞内运输的累积惯性的现象，涉及多个电机蛋白在人类上皮细胞通过测量经验的生存概率的货物的微管和他们的脱离率。我们发现，货物在微管上移动的时间越长，它从微管上脱离的可能性就越小，因此，货物的运动是非马尔可夫的，并且涉及记忆。我们观察到记忆效应的规模高达2秒。我们提供了一个理论之间的联系测得的脱离率和超扩散利维步行样货物运动。
英文摘要：
We demonstrate the phenomenon of cumulative inertia in intracellular transport involving multiple motor proteins in human epithelial cells by measuring the empirical survival probability of cargoes on the microtubule and their detachment rates. We found the longer a cargo moves along a microtubule, the less likely it detaches from it. As a result, the movement of cargoes is non-Markovian and involves a memory. We observe memory effects on the scale of up to 2 seconds. We provide a theoretical link between the measured detachment rate and the super-diffusive Levy walk-like cargo movement.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
