具有PB/cm^3密度、高度并行的读/写操作和真正的3D存储能力的大分子数据存储
Macro-molecular data storage with petabyte/cm^3 density, highly parallel read/write operations, and genuine 3D storage capability
摘要：
数字信息可以被编码在大分子（如RNA和单链DNA）的构建块序列中。“写入”和“读取”大分子链的方法目前是可用的，但它们缓慢且昂贵。在理想的分子数据存储系统中，诸如写入、读取、擦除、存储和传输的常规操作必须在集成芯片内可靠地且高速地完成。作为证明这一概念的可行性的第一步，我们报告了在小型化的腔室中进行的DNA读出实验的初步结果，这些腔室可以扩展到更小的尺寸。我们表明，易位的单链DNA分子（由50个腺苷碱基，随后由100个胞嘧啶碱基组成）通过离子通道产生的特征信号，这是由于分子的2段结构。我们还研究了依赖的速率和速度的分子易位的可调参数的实验。
英文摘要：
Digital information can be encoded in the building-block sequence of macro-molecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive. In an ideal molecular data storage system, routine operations such as write, read, erase, store, and transfer must be done reliably and at high speed within an integrated chip. As a first step toward demonstrating the feasibility of this concept, we report preliminary results of DNA readout experiments conducted in miniaturized chambers that are scalable to even smaller dimensions. We show that translocation of a single-stranded DNA molecule (consisting of 50 adenosine bases followed by 100 cytosine bases) through an ion-channel yields a characteristic signal that is attributable to the 2-segment structure of the molecule. We also examine the dependence of the rate and speed of molecular translocation on the adjustable parameters of the experiment.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
