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arXiv 1704.08583q-bio.PEcond-mat.stat-mech
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Petri Torus中多重耐药性的产生模型

A Model for Emergence of Multiple Anti-Microbial Resistance in a Petri Torus

Roberto C. Alamino

摘要:

本工作介绍了一种新的统计物理晶格模型的细菌与抗微生物药物的相互作用,可以重现定性特征的耐药性出现,其模型参数和输出可以测量与控制\textit{in vitro}实验。晶格是由伊辛感知器建模的代理居住。结果表明,与其他治疗方案相比,在人群中混合药物的优势。

英文摘要:

This work introduces a new statistical physics lattice model of bacteria interacting with anti-microbial drugs that can reproduce qualitative features of resistance emergence and whose model parameters and outputs can be measured with controlled \textit{in vitro} experiments. The lattice is inhabited by agents modeled by Ising perceptrons. The results show the advantage of mixing drugs among the population compared to other treatment protocols.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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