We study triangulated surface models with nontrivial surface metrices for membranes. The surface model is defined by a mapping ${\bf r}$ from a two dimensional parameter space $M$ to the three dimensional Euclidean space ${\bf R}^3$. The metric variable $g_{ab}$, which is always fixed to the Euclidean metric $δ_{ab}$, can be extended to a more general non-Euclidean metric on $M$ in the continuous model. The problem we focus on in this paper is whether such an extension is well-defined or not in the discrete model. We find that a discrete surface model with nontrivial metric becomes well-defined if it is treated in the context of Finsler geometry (FG) modeling, where triangle edge length in $M$ depends on the direction. It is also shown that the discrete FG model is orientation assymetric on invertible surfaces in general, and for this reason, the FG model has a potential advantage for describing real physical membranes, which are expected to have some assymetries for orientation changing transformations.
F1 rotary motor of ATP synthase is driven by the torsionally-asymmetric drive shaft
F1 F0 ATP合酶(ATP酶)在质子移动力(pmf)驱动的过程中促进线粒体膜和细菌内膜中ATP的合成,或者使用来自ATP水解的能量来逆着浓度梯度泵送质子穿过膜。ATP酶由两个旋转马达F0和F1组成,它们产生相反的旋转并竞争对它们共享的中央γ轴的控制。在这里,我们基于线圈γ轴扭转弹性能的不对称性,将F1电机的自洽物理模型描述为简化的两态布朗棘轮。该随机模型统一了直线电机和旋转电机的物理描述,并解释了$γ$ -轴的步进单向旋转,与Boyer的“绑定变化”思想一致。替代模型参数,所有独立已知从最近的实验中,我们的模型定量再现的ATP酶的操作,例如,“空载”角速度是ca。400~rad/s的抗张强度与实验结果基本一致。增加由F0施加的pmf扭矩可以减慢、停止和克服由F1产生的扭矩,以非常低的“失速扭矩”值从ATP水解切换到合成。我们讨论的问题的电机效率,这是非常低的,如果计算从有用的机械工作,它产生的-但相当高的“有用的结果”时,被衡量的数量H+推动对化学梯度在F1 ATP驱动的操作。
Liquid crystalline order and its impact on shape evolution of fluid lipid membranes
Technische Universität Dresden(德累斯顿工业大学);Institut für Wissenschaftliches Rechnen, Technische Universität Dresden(德累斯顿大学科学计算研究所);Center for Systems Biology Dresden (CSBD)(德累斯顿系统生物学中心);Cluster of Excellence Physics of Life (PoL), Technische Universität Dresden(德累斯顿大学生命物理卓越集群)
Asymmetric electrostatic properties of an electric double layer: a generalized Poisson-Boltzmann approach taking into account non-uniform size effects and water polarization