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arXiv 1702.07019cs.CV
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基于感知深度神经网络的CT图像去噪

CT Image Denoising with Perceptive Deep Neural Networks

Rensselaer Polytechnic Institute(伦斯勒理工学院);Philips Research North America(飞利浦北美研究院);Massachusetts General Hospital(麻省总医院);Harvard Medical School(哈佛医学院)

Qingsong Yang, Pingkun Yan, Mannudeep K. Kalra, Ge Wang

摘要:

在现代医学实践中越来越多地使用CT,引起了对相关辐射剂量的关注。减少与CT相关的辐射剂量会增加噪声和伪影,这会对诊断信心产生不利影响。另一方面,低剂量CT图像的去噪可以帮助提高诊断置信度,然而,由于其不适定性质,这是一个具有挑战性的问题,因为一个噪声图像块可能对应于许多不同的输出块。在过去的十年中,基于机器学习的方法在这个方向上取得了令人印象深刻的进展。然而,这些方法中的大多数,包括最近流行的深度学习技术,旨在最小化去噪CT图像和地面实况之间的均方误差(MSE),这导致由于过度平滑而丢失重要的结构细节,尽管基于PSNR的性能测量看起来很棒。在这项工作中,我们引入了一种新的感知相似性度量作为深度卷积神经网络的目标函数,以促进CT图像去噪。我们不是直接计算像素到像素强度损失的MSE,而是将去噪输出的感知特征与特征空间中的地面真值进行比较。因此,我们所提出的方法不仅能够降低图像噪声水平,但也保持了关键的结构信息在同一时间。在大量CT图像的实验中,取得了令人满意的结果。

英文摘要:

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising of low-dose CT images on the other hand can help improve diagnostic confidence, which however is a challenging problem due to its ill-posed nature, since one noisy image patch may correspond to many different output patches. In the past decade, machine learning based approaches have made quite impressive progress in this direction. However, most of those methods, including the recently popularized deep learning techniques, aim for minimizing mean-squared-error (MSE) between a denoised CT image and the ground truth, which results in losing important structural details due to over-smoothing, although the PSNR based performance measure looks great. In this work, we introduce a new perceptual similarity measure as the objective function for a deep convolutional neural network to facilitate CT image denoising. Instead of directly computing MSE for pixel-to-pixel intensity loss, we compare the perceptual features of a denoised output against those of the ground truth in a feature space. Therefore, our proposed method is capable of not only reducing the image noise levels, but also keeping the critical structural information at the same time. Promising results have been obtained in our experiments with a large number of CT images.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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