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arXiv 1702.01568q-bio.NC
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从前馈和递归回路模型解释相关神经变异性

Interpretation of Correlated Neural Variability from Models of Feed-Forward and Recurrent Circuits

Volker Pernice, Rava Azeredo da Silveira

摘要:

神经元群体对感觉刺激的重复呈现的响应的相关变化是普遍观察到的现象。这种相关性已被研究得非常详细,无论是在其机械的起源和他们的影响,刺激歧视和人口的表现代码。特别地,递归神经网络模型已被用于理解神经活动中相关性的起源(或缺乏)。在这里,我们应用一个模型的递归连接的随机神经元来解释相关性,发现在一个人口的神经元记录从小鼠听觉皮层。我们研究了相关性的刺激依赖性上的经常性连接的后果,并将其与相关性变化的替代来源(如相关增益波动和前馈架构中的共同输入)进行比较。我们发现,具有随机有效连接的递归网络模型以自然的方式再现了观察到的统计数据,例如数据中噪声和信号相关性之间的关系。在该模型中,我们可以直接分析网络参数之间的关系,相关性,以及如何根据人口活动来区分刺激对。这样,我们就可以把电路参数与信息处理联系起来。

英文摘要:

The correlated variability in the responses of a neural population to the repeated presentation of a sensory stimulus is a universally observed phenomenon. Such correlations have been studied in much detail, both with respect to their mechanistic origin and to their influence on stimulus discrimination and on the performance of population codes. In particular, recurrent neural network models have been used to understand the origin (or lack) of correlations in neural activity. Here, we apply a model of recurrently connected stochastic neurons to interpret correlations found in a population of neurons recorded from mouse auditory cortex. We study the consequences of recurrent connections on the stimulus dependence of correlations, and we compare them to those from alternative sources of correlated variability, like correlated gain fluctuations and common input in feed-forward architectures. We find that a recurrent network model with random effective connections reproduces observed statistics, like the relation between noise and signal correlations in the data, in a natural way. In the model, we can analyze directly the relation between network parameters, correlations, and how well pairs of stimuli can be discriminated based on population activity. In this way, we can relate circuit parameters to information processing.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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