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arXiv 1612.09486q-bio.TOphysics.med-ph
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非生理血压〈动〉<动>伪影对脑自动调节测量的影响

Effects of non-physiological blood pressure artefacts on measures of cerebral autoregulation

Adam Mahdi, Erica Rutter, Stephen J. Payne

摘要:

脑自身调节是指旨在维持脑血流大致恒定的调节机制。通常通过自动调节指数(ARI)进行评估,该指数使用动脉血压〈动〉<动>和脑血流速度时间序列来产生自动调节性能的十标度指数(0表示不存在自动调节,9表示最强自动调节)。不幸的是,数据很少没有各种人为因素。在这里,我们考虑四个最常见的非生理血压〈动〉<动>伪影(饱和度,方波,降低脉压和脉冲),并研究其对ARI的影响,为一系列不同的伪影大小。我们表明,一个足够大的饱和度和方波总是导致ARI达到最大值9。脉压降低和脉冲伪影导致更多样化的行为。最后,我们描述了伪影的临界尺寸,定义为平均导致ARI偏差10%的最小伪影尺寸

英文摘要:

Cerebral autoregulation refers to regulation mechanisms that aim to maintain cerebral blood flow approximately constant. It is often assessed by autoregulation index (ARI), which uses arterial blood pressure and cerebral blood flow velocity time series to produce a ten-scale index of autoregulation performance (0 denoting the absence of and 9 the strongest autoregulation). Unfortunately, data are rarely free from various artefacts. Here, we consider four of the most common non-physiological blood pressure artefacts (saturation, square wave, reduced pulse pressure and impulse) and study their effects on ARI for a range of different artefact sizes. We show that a sufficiently large saturation and square wave always result in ARI reaching the maximum value of 9. The pulse pressure reduction and impulse artefact lead to a more diverse behaviour. Finally, we characterised the critical size of artefacts, defined as the minimum artefact size that, on average, leads to a 10\% deviation of ARI

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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