人类连接组计划数据中相对脑区的性别二态性
Human Sexual Dimorphism of the Relative Cerebral Area Volumes in the Data of the Human Connectome Project
摘要:
男性的平均人脑体积大于女性。几个基于MRI体素的形态学研究表明,女性的灰质/白质比例较大。在这里,我们分析了最近公开发布的人类连接组计划,并通过使用511名受试者(209名男性和302名女性)的弥散MRI数据,我们发现,许多皮质下区域和大多数皮质区域的灰质的相对体积在女性中明显大于男性。此外,我们还发现了不同半球的相同结构之间的性相关强度的差异。
英文摘要:
The average human brain volume of the males is larger than that of the females. Several MRI voxel-based morphometry studies show that the gray matter/white matter ratio is larger in females. Here we have analyzed the recent public release of the Human Connectome Project, and by using the diffusion MRI data of 511 subjects (209 men and 302 women), we have found that the relative volumes of numerous subcortical areas and the gray matter of most cortical areas are significantly larger in women than in men. Additionally, we have discovered differences of the strengths of the sexual correlations between the same structures in different hemispheres.
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