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arXiv 1604.02404q-bio.NC
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视觉短时记忆绑定任务中Beta版EEG连接性的网络分析方法比较

Comparison of Network Analysis Approaches on EEG Connectivity in Beta during Visual Short-Term Memory Binding Tasks

Keith Smith, Hamed Azami, Mario A. Parra, Javier Escudero, John M. Starr

摘要:

我们分析了记录的年轻健康志愿者的工作记忆表征的β带中的脑电图信号,这些志愿者执行几种不同的视觉短期记忆(VSTM)任务,这些任务已被证明在临床和临床前阿尔茨海默病的评估中是有用的。我们比较网络分析使用最大生成树(MSTs)与网络分析使用20%和25%的连接阈值的VSTM数据。MST是一种很有前途的网络分析方法,否定了迄今为止任意选择的阈值的更经典的使用。然而,我们发现阈值分析优于MST检测功能网络的差异。特别是,MST没有发现任何显著差异。此外,当在显示屏的左侧测试形状和形状-颜色结合任务时,阈值检测到这些任务之间的显著差异,但是当在显示屏的右侧测试这些任务时,没有检测到这样的差异。这提供了证据表明,对侧活动是一个重要的因素,检测认知任务的差异的灵敏度。

英文摘要:

We analyse the electroencephalogram signals in the beta band of working memory representation recorded from young healthy volunteers performing several different Visual Short-Term Memory (VSTM) tasks which have proven useful in the assessment of clinical and preclinical Alzheimer's disease. We compare network analysis using Maximum Spanning Trees (MSTs) with network analysis obtained using 20% and 25% connection thresholds on the VSTM data. MSTs are a promising method of network analysis negating the more classical use of thresholds which are so far chosen arbitrarily. However, we find that the threshold analyses outperforms MSTs for detection of functional network differences. Particularly, MSTs fail to find any significant differences. Further, the thresholds detect significant differences between shape and shape-colour binding tasks when these are tested in the left side of the display screen, but no such differences are detected when these tasks are tested for in the right side of the display screen. This provides evidence that contralateral activity is a significant factor in sensitivity for detection of cognitive task differences.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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