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arXiv 1603.06142q-bio.PEq-bio.QM
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如何评价慢性病病例发现:不同指标的比较

How to assess case-finding in chronic diseases: Comparison of different indices

Ralph Brinks

摘要:

最近,我们提出了一个新的疾病-死亡模型,其中包括一个未确诊的慢性疾病的状态之前,已确诊的疾病。根据这一模式,出现了一个问题,即在所有这些州都存在死亡率的情况下,如何评估病例发现。我们模拟了两种不同的情况下的病例发现的性能,并应用几个指标来评估在这两种情况下的病例发现。基于流行率的指数之一导致错误的结论。部分指标对区分病例发现质量不敏感。基于发病率的指数表现良好。如果可能,应首选基于发病率的指数。

英文摘要:

Recently, we have proposed a new illness-death model that comprises a state of undiagnosed chronic disease preceding the diagnosed disease. Based on this model, the question arises how case-finding can be assessed in the presence of mortality from all these states. We simulate two scenarios of different performance of case-finding and apply several indices to assess case-finding in both scenarios. One of the prevalence based indices leads to wrong conclusions. Some indices are partly insensitive to distinguish the quality of case-finding. The incidence based indices perform well. If possible, incidence based indices should be preferred.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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