细菌细胞丝状体的自伸长和连续折叠
Self-Elongation with Sequential Folding of a Filament of Bacterial Cells
摘要:
在硬琼脂和营养丰富的条件下,由于在每个生长和分裂周期后细胞分离失败,$Bacillus$ $subtilis$的细胞作为单丝生长。细胞的自伸长细丝显示连续的折叠过程,并且多折叠结构在琼脂平板上延伸。我们报告的生长过程中,从指数阶段的稳定期是很好地描述了分形维数的时间演变的细丝配置。我们提出了一种方法,使用一组长度的多倍部分的灯丝配置的特征。微分方程系统被引入来描述在生长过程的早期阶段产生多重结构的折叠过程。我们表明,实验数据的拟合方程的解决方案是优秀的,并在我们的模型系统中所涉及的参数确定。
英文摘要:
Under hard-agar and nutrient-rich conditions, a cell of $Bacillus$ $subtilis$ grows as a single filament owing to the failure of cell separation after each growth and division cycle. The self-elongating filament of cells shows sequential folding processes, and multifold structures extend over an agar plate. We report that the growth process from the exponential phase to the stationary phase is well described by the time evolution of fractal dimensions of the filament configuration. We propose a method of characterizing filament configurations using a set of lengths of multifold parts of a filament. Systems of differential equations are introduced to describe the folding processes that create multifold structures in the early stage of the growth process. We show that the fitting of experimental data to the solutions of equations is excellent, and the parameters involved in our model systems are determined.,
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