SWEEPFINDER2：提高灵敏度、稳健性和灵活性
SWEEPFINDER2: Increased sensitivity, robustness, and flexibility
摘要：
Sweeptool是一个流行的程序，它实现了一个强大的基于似然的方法，用于检测最近的阳性选择或选择性扫描。在这里，我们提出了SweepFinder2，SweepFinder的扩展，增加了灵敏度和鲁棒性的混杂效应的突变率变化和背景选择，以及增加的灵活性，使用户能够更详细地检查基因组区域，并指定一个固定的距离之间的测试站点。此外，SweepFinder2允许使用不变站点进行扫描检测，相对于SweepFinder，提高了其功能和精度。
英文摘要：
SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the confounding effects of mutation rate variation and background selection, as well as increased flexibility that enables the user to examine genomic regions in greater detail and to specify a fixed distance between test sites. Moreover, SweepFinder2 enables the use of invariant sites for sweep detection, increasing both its power and precision relative to SweepFinder.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
