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arXiv 1505.04550math.PR
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不同规模种群中两个突变的相互作用:克隆干扰的随机生态进化模型

The interplay of two mutations in a population of varying size: a stochastic eco-evolutionary model for clonal interference

Sylvain Billiard, Charline Smadi

摘要:

克隆干扰,多个共同发生的有益突变之间的竞争,在无性种群的适应中起着重要作用。我们提供了一个简单的基于个体的克隆干扰随机模型,考虑到各种各样的竞争相互作用,可以在自然界中找到。特别是,我们放松了经典的假设之间的不同突变的传递性。它使我们能够预测遗传模式,如几个突变体的共存或出现的石头剪刀布周期,这是没有解释现有的模型。此外,我们呼吁一些经典的先入为主的想法的问题,固定时间和固定竞争突变的概率。

英文摘要:

Clonal interference, competition between multiple co-occurring beneficial mutations, has a major role in adaptation of asexual populations. We provide a simple individual based stochastic model of clonal interference taking into account a wide variety of competitive interactions which can be found in nature. In particular, we relax the classical assumption of transitivity between the different mutations. It allows us to predict genetic patterns, such as coexistence of several mutants or emergence of Rock-Paper-Scissors cycles, which were not explained by existing models. In addition, we call into questions some classical preconceived ideas about fixation time and fixation probability of competing mutations.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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