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arXiv 1503.06323cs.CV

Wavelet based approach for tissue fractal parameter measurement: Pre cancer detection

Indian Institute of Science Education and Research (IISER) Kolkata(印度科学教育与研究所加尔各答分校);Institute of Engineering & Management, Kolkata(工程与管理学院(加尔各答));Indian Institute of Technology (IIT) Kanpur(印度理工学院坎普尔分校);College of Engineering & Management, Kolaghat(工程与管理学院(科拉加特))

Sabyasachi Mukhopadhyay, Nandan K. Das, Soham Mandal, Sawon Pratiher, Asish Mitra, Asima Pradhan, Nirmalya Ghosh, Prasanta K. Panigrahi

英文摘要:

In this paper, we have carried out the detail studies of pre-cancer by wavelet coherency and multifractal based detrended fluctuation analysis (MFDFA) on differential interference contrast (DIC) images of stromal region among different grades of pre-cancer tissues. Discrete wavelet transform (DWT) through Daubechies basis has been performed for identifying fluctuations over polynomial trends for clear characterization and differentiation of tissues. Wavelet coherence plots are performed for identifying the level of correlation in time scale plane between normal and various grades of DIC samples. Applying MFDFA on refractive index variations of cervical tissues, we have observed that the values of Hurst exponent (correlation) decreases from healthy (normal) to pre-cancer tissues. The width of singularity spectrum has a sudden degradation at grade-I in comparison of healthy (normal) tissue but later on it increases as cancer progresses from grade-II to grade-III.

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