关于编制随机治疗分配表的问题
On Preparing a List of Random treatment Assigns
摘要：
本文介绍了一种面向计算机的方法，用于准备随机对照试验中采用的随机治疗分配列表的基础。介绍了可用于临床试验和生物等效性试验早期阶段的软件。在临床试验中将患者分配到治疗中可确保治疗数量完全相等。对分配的随机性的研究导致了“强随机列表”的概念。本说明中介绍的新方法基于阈值，并产生了一个强有力的治疗分配随机列表。
英文摘要：
This paper presents the foundations of a computer oriented approach for preparing a list of random treatment assignments to be adopted in randomised controlled trials. Software is presented which can be applied in the earliest stage of clinical trials and bioequivalence assays. This allocation of patients to treatment in clinical trials ensures exactly equal treatment numbers. The investigation of the randomness properties of an assignment leads to the concept of a 'strong randomised list'. The new approach introduced in this note is based on thresholds and produces a strong randomised list of treatment assignments.
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