A two-stage approach is proposed to overcome the problem in quantile regression, where separately fitted curves for several quantiles may cross. The standard Bayesian quantile regression model is applied in the first stage, followed by a Gaussian process regression adjustment, which monotonizes the quantile function whilst borrowing strength from nearby quantiles. The two stage approach is computationally efficient, and more general than existing techniques. The method is shown to be competitive with alternative approaches via its performance in simulated examples.
Quantile regression models are a powerful tool for studying different points of the conditional distribution of univariate response variables. Their multivariate counterpart extension though is not straightforward, starting with the definition of multivariate quantiles. We propose here a flexible Bayesian quantile regression model when the response variable is multivariate, where we are able to define a structured additive framework for all predictor variables. We build on previous ideas considering a directional approach to define the quantiles of a response variable with multiple-outputs and…
Bayesian simultaneous estimation of nonparametric quantile curves is a challenging problem, requiring a flexible and robust data model whilst satisfying the monotonicity or noncrossing constraints on the quantiles. This paper presents the use of the pyramid quantile regression method in the spline regression setting. In high dimensional problems, the choice of the pyramid locations becomes crucial for a robust parameter estimation. In this work we derive the optimal {pyramid locations which then allows us to propose an efficient} adaptive block-update MCMC scheme for posterior computation. Sim…
Quantile regression is a powerful data analysis tool that accommodates heterogeneous covariate-response relationships. We find that by coupling the asymmetric Laplace working likelihood with appropriate shrinkage priors, we can deliver posterior inference that automatically adapts to possible sparsity in quantile regression analysis. After a suitable adjustment on the posterior variance, the posterior inference provides asymptotically valid inference under heterogeneity. Furthermore, the proposed approach leads to oracle asymptotic efficiency for the active (nonzero) quantile regression coeffi…
A common method for assessing validity of Bayesian sampling or approximate inference methods makes use of simulated data replicates for parameters drawn from the prior. Under continuity assumptions, quantiles of functions of the simulated parameter values within corresponding posterior distributions are uniformly distributed. Checking for uniformity when a posterior density is approximated numerically provides a diagnostic for algorithm validity. Furthermore, adjustments to achieve uniformity can improve the quality of approximate inference methods. A weakness of this general approach is that …
With continuous outcomes, the average causal effect is typically defined using a contrast of expected potential outcomes. However, in the presence of skewed outcome data, the expectation may no longer be meaningful. In practice the typical approach is to either "ignore or transform" - ignore the skewness altogether or transform the outcome to obtain a more symmetric distribution, although neither approach is entirely satisfactory. Alternatively the causal effect can be redefined as a contrast of median potential outcomes, yet discussion of confounding-adjustment methods to estimate this parame…
University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；MIT（麻省理工学院）
We develop Temporal Quantile Adjustment (TQA), a general method to construct efficient and valid prediction intervals (PIs) for regression on cross-sectional time series data. Such data is common in many domains, including econometrics and healthcare. A canonical example in healthcare is predicting patient outcomes using physiological time-series data, where a population of patients composes a cross-section. Reliable PI estimators in this setting must address two distinct notions of coverage: cross-sectional coverage across a cross-sectional slice, and longitudinal coverage along the temporal …
Department of Mathematics University of California San Diego（加利福尼亚大学圣地亚哥分校数学系）
Random forests are powerful non-parametric regression method but are severely limited in their usage in the presence of randomly censored observations, and naively applied can exhibit poor predictive performance due to the incurred biases. Based on a local adaptive representation of random forests, we develop its regression adjustment for randomly censored regression quantile models. Regression adjustment is based on new estimating equations that adapt to censoring and lead to quantile score whenever the data do not exhibit censoring. The proposed procedure named censored quantile regression f…
Quantile regression provides a consistent approach to investigating the association between covariates and various aspects of the distribution of the response beyond the mean. When the regression covariates are measured with errors, measurement error (ME) adjustment steps are needed for valid inference. This is true for both scalar and functional covariates. Here, we propose extending the Bayesian measurement error and Bayesian quantile regression literature to allow for available covariates prone to potential complex measurement errors. Our approach uses the Generalized Asymmetric Laplace (GA…
Mass spectrometry proteomics, characterized by spiky, spatially heterogeneous functional data, can be used to identify potential cancer biomarkers. Existing mass spectrometry analyses utilize mean regression to detect spectral regions that are differentially expressed across groups. However, given the inter-patient heterogeneity that is a key hallmark of cancer, many biomarkers are only present at aberrant levels for a subset of, not all, cancer samples. Differences in these biomarkers can easily be missed by mean regression, but might be more easily detected by quantile-based approaches. Thus…
Quantile regression is an increasingly important empirical tool in economics and other sciences for analyzing the impact of a set of regressors on the conditional distribution of an outcome. Extremal quantile regression, or quantile regression applied to the tails, is of interest in many economic and financial applications, such as conditional value-at-risk, production efficiency, and adjustment bands in (S,s) models. In this paper we provide feasible inference tools for extremal conditional quantile models that rely upon extreme value approximations to the distribution of self-normalized quan…
Datasets from field experiments with covariate-adaptive randomizations (CARs) usually contain extra covariates in addition to the strata indicators. We propose to incorporate these additional covariates via auxiliary regressions in the estimation and inference of unconditional quantile treatment effects (QTEs) under CARs. We establish the consistency and limit distribution of the regression-adjusted QTE estimator and prove that the use of multiplier bootstrap inference is non-conservative under CARs. The auxiliary regression may be estimated parametrically, nonparametrically, or via regulariza…
Standard causal inference characterizes treatment effect through averages, but the counterfactual distributions could be different in not only the central tendency but also spread and shape. To provide a comprehensive evaluation of treatment effects, we focus on estimating quantile treatment effects (QTEs). Existing methods that invert a nonsmooth estimator of the cumulative distribution functions forbid inference on probability density functions (PDFs), but PDFs can reveal more nuanced characteristics of the counterfactual distributions. We adopt a semiparametric conditional distribution regr…
