arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 1407.3010stat.MEstat.ML
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基于稀疏聚类的双聚类

Biclustering Via Sparse Clustering

Qian Liu, Guanhua Chen, Michael R. Kosorok, Eric Bair

摘要:

在许多情况下,需要识别仅在特征的子集方面不同的聚类。这样的聚类可以表示患有疾病(诸如癌症或慢性疼痛)的患者的同质亚组。我们将双聚类定义为较大数据矩阵X的子矩阵U,使得U中的特征和观测不同于U中不包含的特征和观测。例如,U中的观测相对于U中的要素可能具有不同的均值或方差。我们基于Witten和Tibshirani(2010)的稀疏聚类方法提出了一个通用的双聚类框架。我们开发了一种方法来识别属于biclusters的功能。该框架可以用于识别在特征的均值、特征的方差或更一般的差异方面不同的双聚类。我们将这些方法应用于几个模拟和真实世界的数据集,并将我们的方法与以前发表的几种方法的结果进行比较。我们的方法与现有的方法相比,在预测精度和计算时间方面的结果毫不逊色。

英文摘要:

In many situations it is desirable to identify clusters that differ with respect to only a subset of features. Such clusters may represent homogeneous subgroups of patients with a disease, such as cancer or chronic pain. We define a bicluster to be a submatrix U of a larger data matrix X such that the features and observations in U differ from those not contained in U. For example, the observations in U could have different means or variances with respect to the features in U. We propose a general framework for biclustering based on the sparse clustering method of Witten and Tibshirani (2010). We develop a method for identifying features that belong to biclusters. This framework can be used to identify biclusters that differ with respect to the means of the features, the variance of the features, or more general differences. We apply these methods to several simulated and real-world data sets and compare the results of our method with several previously published methods. The results of our method compare favorably with existing methods with respect to both predictive accuracy and computing time.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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