基于持久图的参数推断:群体遗传学的一个实例
Parametric Inference using Persistence Diagrams: A Case Study in Population Genetics
摘要:
持久同源从点云数据计算拓扑不变量。最近的工作重点是在这一框架内制定数据分析的统计方法。我们表明,在某些模型中,参数推断可以使用统计定义的计算不变量。我们用一个来自群体遗传学的模型发展了这个想法,即结合与重组。我们将我们的模型应用于流感数据集,确定了两个尺度的拓扑结构,具有不同的生物学解释。
英文摘要:
Persistent homology computes topological invariants from point cloud data. Recent work has focused on developing statistical methods for data analysis in this framework. We show that, in certain models, parametric inference can be performed using statistics defined on the computed invariants. We develop this idea with a model from population genetics, the coalescent with recombination. We apply our model to an influenza dataset, identifying two scales of topological structure which have a distinct biological interpretation.
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