收缩驱动爬行的最优性
Optimality of contraction-driven crawling
摘要：
我们研究了一个模型的细胞运动性能和代谢成本之间的最佳权衡的条件可以精确。在这个模型中，一个稳定的爬行片段是由一层活性凝胶放在摩擦表面上，并仅由收缩驱动。我们分析发现，可收缩元件（牵引器）的分布确保了自推进的效率是最大的。然后，我们表明，自然的假设对流和扩散的拖拉机产生的分布，是非常接近的最佳的，是定性类似的实验中观察到的鱼角膜细胞。
英文摘要：
We study a model of cell motility where the condition of optimal trade-off between performance and metabolic cost can be made precise. In this model a steadily crawling fragment is represented by a layer of active gel placed on a frictional surface and driven by contraction only. We find analytically the distribution of contractile elements (pullers) ensuring that the efficiency of self-propulsion is maximal. We then show that natural assumptions about advection and diffusion of pullers produce a distribution that is remarkably close to the optimal one and is qualitatively similar to the one observed in experiments on fish keratocytes.
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