从一个特殊势计算Canham-Helfrich自由能量密度的弯曲模量
Calculating the bending moduli of the Canham--Helfrich free-energy density from a particular potential
摘要:
脂质双层的Canham-Helfrich自由能量密度涉及双层中表面的平均曲率和高斯曲率。张开和鞍形张开模量$κ$和$\barκ$调节自由能量密度对这些曲率变化的灵敏度。Seguin和Fried通过考虑组成双层的分子之间的相互作用推导出了Canham-Helfrich能量,从而产生了相互作用势中模量的积分表示。在目前的工作中,两个潜在的选择和积分进行评估,以产生表达式的模量,这被发现取决于与每个潜在的参数。这些结果进行了比较,在目前的文献中发现的模量值。
英文摘要:
The Canham--Helfrich free-energy density for a lipid bilayer involves the mean and Gaussian curvatures of the midsurface of the bilayer. The splay and saddle-splay moduli $κ$ and $\barκ$ regulate the sensitivity of the free-energy density to changes of these curvatures. Seguin and Fried derived the Canham--Helfrich energy by taking into account the interactions between the molecules comprising the bilayer, giving rise to integral representations for the moduli in terms of the interaction potential. In the present work, two potentials are chosen and the integrals are evaluated to yield expressions for the moduli, which are found to depend on parameters associated with each potential. These results are compared with values of the moduli found in the current literature.
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