MPLomics：用于多患者基因组标记分析的R软件包
MPAgenomics : An R package for multi-patients analysis of genomic markers
摘要：
MPTomics，代表基因组标记的多患者分析（MPA），是一个R包，致力于：（i）有效分割，和（ii）从多患者拷贝数和SNP数据谱中选择基因组标记。它提供了来自常用包的包装器，以方便它们的重复（有时很难）使用，为R初学者提供了一个易于使用的管道。连续多个配置文件的分割（发现损失和收益）是基于一个新的自动选择的影响参数，因为默认的是在原来的包误导。同时考虑多个配置文件，MPPomics包装了有效的惩罚回归方法，以选择与给定响应相关的相关标记。
英文摘要：
MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. It provides wrappers from commonly used packages to facilitate their repeated (sometimes difficult) use, offering an easy-to-use pipeline for beginners in R. The segmentation of successive multiple profiles (finding losses and gains) is based on a new automatic choice of influential parameters since default ones were misleading in the original packages. Considering multiple profiles in the same time, MPAgenomics wraps efficient penalized regression methods to select relevant markers associated with a given response.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
