模式驱动的生物医学本体工程方法
A pattern-driven approach to biomedical ontology engineering
摘要：
开发本体可能是昂贵的，耗时的，以及难以开发和维护。这对于更具表达性和/或更大的本体尤其如此。然而，一些本体是相对重复的，重用设计模式;用通用和定制模式构建这些本体应该减少重复并增加规律性，这反过来会影响开发成本。在这里，我们报告的使用模式应用于两个生物医学本体：首先是一个新的本体的核型已建成地面使用基于模式的方法，其次，我们最初的重构的SIO本体，使明确使用的模式在开发时。为了实现这一点，我们使用Tawny-OWL库，它支持本体的全编程开发。我们展示了这种方法如何从更简单的数据结构中生成大量的类，这在生物医学本体工程中非常有益。
英文摘要：
Developing ontologies can be expensive, time-consuming, as well as difficult to develop and maintain. This is especially true for more expressive and/or larger ontologies. Some ontologies are, however, relatively repetitive, reusing design patterns; building these with both generic and bespoke patterns should reduce duplication and increase regularity which in turn should impact on the cost of development. Here we report on the usage of patterns applied to two biomedical ontologies: firstly a novel ontology for karyotypes which has been built ground-up using a pattern based approach; and, secondly, our initial refactoring of the SIO ontology to make explicit use of patterns at development time. To enable this, we use the Tawny-OWL library which enables full-programmatic development of ontologies. We show how this approach can generate large numbers of classes from much simpler data structures which is highly beneficial within biomedical ontology engineering.
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