突触的后可塑性是拟南芥强直性增强的基础:一个新的范例
Synaptic metaplasticity underlies tetanic potentiation in Lymnaea: a novel paradigm
摘要:
我们提出了一个数学模型,解释和解释了一种新的形式的短期增强,这被发现是使用,但不依赖于时间,在实验中完成的神经元。高度的增强解释使用模型的突触后可塑性,而使用依赖性(这是严重依赖于在实验中的激酶的存在下)解释使用模型的随机性和生物学开关。
英文摘要:
We present a mathematical model which explains and interprets a novel form of short-term potentiation, which was found to be use-, but not time-dependent, in experiments done on Lymnaea neurons. The high degree of potentiation is explained using a model of synaptic metaplasticity, while the use-dependence (which is critically reliant on the presence of kinase in the experiment) is explained using a model of a stochastic and bistable biological switch.
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