Drake规则作为接近航道通过能力的结果
Drake's Rule as a Consequence of Approaching Channel Capacity
摘要：
突变如何在基因组中积累是分子进化理论的中心问题，然而我们对这一过程的理解还远远没有完成。德雷克法则是从微生物到哺乳动物的基因组的众所周知的普遍性质-在一个门内，每代每个基因组的（功能性）突变的数量近似恒定，尽管基因组大小和不同种群特性存在数量级差异。到目前为止，对这种现象还没有简明的解释。遗传信息存储的一个正式模型表明，任何物种的基因组都在其最大信息存储容量附近运行，并且突变率接近其上限，这为该规则提供了一个简单的解释。
英文摘要：
How mutations accumulate in genomes is the central question of molecular evolution theories, however our understanding of this process is far from complete. Drake's rule is a notoriously universal property of genomes from microbes to mammals - the number of (functional) mutations per-genome per-generation is approximately constant within a phylum, despite orders of magnitude differences in genome sizes and diverse populations properties. So far there is no concise explanation for this phenomenon. A formal model of storage of genetic information suggests that a genome of any species operates near its maximum informational storage capacity, and the mutation rate is near its upper limit, providing a simple explanation for the rule with minimal assumptions.
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