Alzheimer's disease is a human brain disease that affects a significant fraction of the population by causing problems with short-term memory, thinking, spatial orientation and behavior, memory loss and other intellectual abilities. Up to date there is no singular test that can definitively diagnose Alzheimer's disease, although imaging technology designed to detect Alzheimer's plaques and tangles is rapidly becoming more powerful and precise. In this paper we introduce a decision-making model, based on the combination of mitochondrial hypothesis-dynamics with the role of electromagnetic influences of the metal ions into the inner mitochondrial membrane and the quantitative analysis of mitochondrial population. While there are few disappointing clinical-trial results for drug treatments in patients with Alzheimer's disease, scientific community need alternative diagnostic tools rather investing mainly in amyloid-targeting drugs.
Soft-Weighted CrossEntropy Loss for Continous Alzheimer's Disease Detection
Beijing JiaoTong University（北京交通大学）；Research Center of 6G Mobile Communications（6G移动通信研究中心）；School of Cyber Science and Engineering（网络空间与工程学院）；Huazhong University of Science and Technology（华中科技大学）
Characterize the non-Gaussian diffusion property of cerebrospinal fluid using Diffusion Kurtosis Imaging and explore its diagnostic efficacy for Alzheimer's disease
A whole-brain model of amyloid beta accumulation and cerebral hypoperfusion in Alzheimer's disease
Politecnico di Milano（米兰理工大学）；University of Vienna（维也纳大学）；University of Oxford（牛津大学）；Friedrich-Alexander-Universität Erlangen-Nürnberg（埃尔朗根-纽伦堡大学）；Stanford University（斯坦福大学）
