多标准分步发射IMRT治疗计划的可扩展导航
Deliverable navigation for multicriteria step and shoot IMRT treatment planning
摘要：
我们考虑基于帕累托曲面的多准则优化的步进和拍摄调强放射治疗计划。通过分析两种导航算法，我们在理论上和实践中表明，在导航过程中形成凸组合的计划所需的计划的数量可以保持很小（远小于理论上的最大数量一般需要，这是等于表面帕累托导航的目标的数量）。因此，在此设置中，直接可交付导航的可行方法是分割基础帕累托曲面计划，然后强制执行温和的限制，即在计划导航期间的任何时候只有少数计划处于活动状态，从而限制最终计划中使用的分段总数。
英文摘要：
We consider Pareto surface based multi-criteria optimization for step and shoot IMRT planning. By analyzing two navigation algorithms, we show both theoretically and in practice that the number of plans needed to form convex combinations of plans during navigation can be kept small (much less than the theoretical maximum number needed in general, which is equal to the number of objectives for on-surface Pareto navigation). Therefore a workable approach for directly deliverable navigation in this setting is to segment the underlying Pareto surface plans and then enforce the mild restriction that only a small number of these plans are active at any time during plan navigation, thus limiting the total number of segments used in the final plan.
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