张力圆柱膜上极性活性丝的图案化
Patterning of polar active filaments on a tense cylindrical membrane
摘要:
我们研究的动态和图案的极性收缩丝的表面上的圆柱形细胞使用主动流体动力学方程,将曲率和细丝取向之间的耦合。索和环自发地出现在圆柱体上作为稳态配置,并且可以是静止的或移动的,螺旋形的或沿着螺旋形轨迹移动的段。收缩诱导近端环的聚结。我们观察到相变的稳态模式时,改变细胞直径,并作出几个可测试的预测。我们的研究结果与圆柱形细胞中各种活性生物聚合物的动力学和图案化有关。
英文摘要:
We study the dynamics and patterning of polar contractile filaments on the surface of a cylindrical cell using active hydrodynamic equations that incorporate couplings between curvature and filament orientation. Cables and rings spontaneously emerge as steady state configurations on the cylinder, and can be stationary or moving, helical or segments moving along helical trajectories. Contractility induces coalescence of proximal rings. We observe phase transitions in the steady state patterns upon changing cell diameter and make several testable predictions. Our results are relevant to the dynamics and patterning of a variety of active biopolymers in cylindrical cells.
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