80 MeV/u碳离子束辐照PMMA产生β ~+发射体的时空分布研究
Study of the time and space distribution of beta+ emitters from 80 MeV/u carbon ion beam irradiation on PMMA
摘要:
质子和碳离子疗法是用于治疗实体癌的新兴技术。在这样的治疗过程中提供的剂量的监测和布拉格峰位置的在线知识仍然是一个研究的问题。一种可能的技术利用了由正电子湮灭产生的共线$511\ \kilo\electronvolt$光子,该正电子湮灭来自由光束产生的$511\ \kilo\electronvolt$发射器。本文报道了在INFN的南国家实验室(LNS)上,$80\ \mega\electronvolt / u$完全剥离的碳离子束与聚甲基丙烯酸甲酯靶相互作用后发射的$511\ \kilo\electronvolt$光子的速率测量。参数化$β^+$速率的时间演变,并观察$^{11}C$发射体相对于其他种类($^{13}N$、$^{15}O$、$^{14}O$)的优势,测量碳离子活化$β^+$发射体$A_0=(10.3\pm0.7)\cdot10^{-3}$的分数。还测量了来自$β^+$发射体的正电子湮灭在PMMA中的平均深度$D_{β^+}=5.3\pm1.1\ \milli\meter$,以与从模拟获得的预期布拉格峰深度$D_{Bragg}=11.0\pm 0.5\ \milli\meter$进行比较。
英文摘要:
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research. A possible technique exploits the collinear $511\ \kilo\electronvolt$ photons produced by positrons annihilation from $β^+$ emitters created by the beam. This paper reports rate measurements of the $511\ \kilo\electronvolt$ photons emitted after the interactions of a $80\ \mega\electronvolt / u$ fully stripped carbon ion beam at the Laboratori Nazionali del Sud (LNS) of INFN, with a Poly-methyl methacrylate target. The time evolution of the $β^+$ rate was parametrized and the dominance of $^{11}C$ emitters over the other species ($^{13}N$, $^{15}O$, $^{14}O$) was observed, measuring the fraction of carbon ions activating $β^+$ emitters $A_0=(10.3\pm0.7)\cdot10^{-3}$. The average depth in the PMMA of the positron annihilation from $β^+$ emitters was also measured, $D_{β^+}=5.3\pm1.1\ \milli\meter$, to be compared to the expected Bragg peak depth $D_{Bragg}=11.0\pm 0.5\ \milli\meter$ obtained from simulations.
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