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arXiv 1109.2893physics.bio-phq-bio.NC
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神经振荡器的多模态转变与兴奋性

Multimodal transition and excitability of a neural oscillator

L. S. Borkowski

AI总结:

本文研究 Morris-Lecar 神经振荡器对周期短脉冲的响应,发现奇数模态到所有模态的多模态转变与 2:1/3:1 双稳态共存,并指出其可能是共振神经元的普遍属性。

摘要:

我们在周期—幅度平面内分析了 Morris-Lecar 模型对短电流脉冲周期序列的响应。在涵盖 Hodgkin 分类中 class 2 和 class 3 行为的宽广参数范围内,奇数模态集合与所有模态集合之间存在一种多模态转变。该转变位于 2:1 和 3:1 锁相区域之间。它与早先在 Hodgkin-Huxley 模型中发现、并在枪乌贼巨轴突中实验观察到的动力学不稳定性相同。在阈值附近区域,它与 2:1 和 3:1 状态的双稳态同时出现。这些结果表明,多模态转变可能是共振神经元的一种普遍属性。

英文摘要:

We analyze the response of the Morris-Lecar model to a periodic train of short current pulses in the period-amplitude plane. For a wide parameter range encompassing both class 2 and class 3 behavior in Hodgkin's classification there is a multimodal transition between the set of odd modes and the set of all modes. It is located between the 2:1 and 3:1 locked-in regions. It is the same dynamic instability as the one discovered earlier in the Hodgkin-Huxley model and observed experimentally in squid giant axons. It appears simultaneously with the bistability of the states 2:1 and 3:1 in the perithreshold regime. These results imply that the multimodal transition may be a universal property of resonant neurons.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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