碳纳米管对蛋白质表面胆固醇结构域的影响
The impact of a carbon nanotube on the cholesterol domain localized on a protein surface
摘要:
利用经典的分子动力学(MD)模拟技术研究了单壁碳纳米管对内皮蛋白1LQV表面胆固醇簇(结构域)结构的影响.我们已经观察到碳纳米管对胆固醇结构域的排列有很大的影响。碳纳米管可以拖出胆固醇分子,显著减少蛋白质上沉积的区域体积。
英文摘要:
The influence of a single walled carbon nanotube on the structure of a cholesterol cluster (domain) developed over the surface of the endothelial protein 1LQV has been investigated using the classical molecular dynamics (MD) simulation technique. We have observed a substantial impact of carbon nanotube on the arrangement of the cholesterol domain. The carbon nanotube can drag out cholesterol molecules, remarkable reducing the volume of the domain settled down on the protein.
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