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arXiv 1009.3072stat.COstat.APstat.ME
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使用Procrustes和配置模型的无标号点集的贝叶斯匹配

Bayesian matching of unlabelled point sets using Procrustes and configuration models

Kim Kenobi, Ian L. Dryden

摘要:

研究了利用贝叶斯推断匹配无标号点集的问题。最近提出的两种模型的可能性进行了比较,根据Procrustes的大小和形状和完整的配置。利用马尔可夫链蒙特卡罗模拟对匹配点集进行贝叶斯推断。改进现有的Procrustes算法,提出了提高收敛速度,偶尔使用大的跳跃在老化期间。的Procrustes和配置方法进行了比较,在模拟研究和使用真实的数据,它是感兴趣的,以估计蛋白质结合位点之间的匹配的强度。这两种方法的性能通常非常相似,并且使用拉普拉斯近似在两个模型之间建立连接。

英文摘要:

The problem of matching unlabelled point sets using Bayesian inference is considered. Two recently proposed models for the likelihood are compared, based on the Procrustes size-and-shape and the full configuration. Bayesian inference is carried out for matching point sets using Markov chain Monte Carlo simulation. An improvement to the existing Procrustes algorithm is proposed which improves convergence rates, using occasional large jumps in the burn-in period. The Procrustes and configuration methods are compared in a simulation study and using real data, where it is of interest to estimate the strengths of matches between protein binding sites. The performance of both methods is generally quite similar, and a connection between the two models is made using a Laplace approximation.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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