东半球双生病毒DNA β卫星重组位点检测的统计分析
Statistical analysis on detecting recombination sites in DNA-beta satellites associated with the old world geminiviruses
摘要：
尽管通过重组进行的遗传信息交换在病毒进化中起着重要作用，但尚不清楚它如何产生多样性。{ \it双生病毒}是具有双义单链环状DNA基因组的植物病毒，并且是农业生产中经济上最重要的植物病毒之一。最近发现小的环状单链DNA卫星，称为DNA- $β$，与一些双生病毒感染有关。本文通过系统发育分析和统计分析，对双生病毒的卫星分子DNA- $β$进行了重组事件分析，发现ToLCMaB的一个毒株具有重组模式，可能是PaLCuB-[IN：Chi：05]（主要亲本）和ToLCB-[IN：CP：04]（次要亲本）两个种毒株之间的重组分子。
英文摘要：
Although an exchange of genetic information by recombination plays an important role in the evolution of viruses, it is not clear how it generates diversity. {\it Geminiviruses} are plant viruses which have ambisense single-stranded circular DNA genomes and one of the most economically important plant viruses in agricultural production. Small circular single-stranded DNA satellites, termed DNA-$β$, have recently been found associated with some geminivirus infections. In this paper we analyze a satellite molecule DNA-$β$ of geminiviruses for recombination events using phylogenetic and statistical analysis and we find that one strain from ToLCMaB has a recombination pattern and is possibly recombinant molecule between two strains from two species, PaLCuB-[IN:Chi:05] (major parent) and ToLCB-[IN:CP:04] (minor parent).
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