等离子体活化烧结制备生物医用多孔钛板
A modified porous titanium sheet prepared by plasma activated sintering for biomedical applications
摘要：
本研究旨在通过在最初开发的TiN涂层石墨模具内的等离子体活化烧结来开发无污染的多孔钛支架。对多孔钛板表面涂覆石墨模具和未涂覆石墨模具进行了表征。本研究还对多孔钛片的细胞黏附性能进行了评价。在用没有TiN涂层的石墨模具加工的钛板上检测到TiC峰。由于钛纤维元件在加工过程中与碳石墨模具直接接触，在这种情况下，表面污染是不可避免的事件。在TiN涂覆的碳石墨模具内处理的钛片上检测不到TiC峰。这种改进的等离子体活化烧结与TiN涂层石墨模具将是有用的，以制造无污染的钛板。贴壁细胞在改性钛板上的数量明显多于裸钛板。在钛片上观察到应力纤维形成和细胞的延伸。这种改性钛片有望成为骨科骨修复的新型组织工程材料。
英文摘要：
This study aimed to develop a contamination free porous titanium scaffold by a plasma activated sintering within an originally developed TiN coated graphite mold. The surface of porous titanium sheet with or without a coated graphite mold was characterized. The cell adhesion property of porous titanium sheet was also evaluated in this study. The peak of TiC was detected on the titanium sheet processed with the graphite mold without a TiN coating. Since the titanium fiber elements were directly in contact with the carbon graphite mold during processing, surface contamination was unavoidable event in this condition. The TiC peak was not detectable on the titanium sheet processed within the TiN coated carbon graphite mold. This modified plasma activated sintering with the TiN coated graphite mold would be useful to fabricate a contamination free titanium sheet. The number of adherent cells on the modified titanium sheet was greater than that of the bare titanium plate. Stress fiber formation and the extension of the cells were observed on the titanium sheets. This modified titanium sheet is expected to be a new tissue engineering material in orthopedic bone repair.
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