生物相容性磁流体的辐射稳定性
Radiation stability of biocompatibile magnetic fluid
摘要：
研究了纳米医学用生物相容性磁流体经电子辐照后的辐射稳定性。制备了两种水基磁流体。第一种是基于一种表面活性剂油酸钠稳定的磁铁矿纳米粒子。第二种是以油酸钠为第一表面活性剂，聚乙二醇（PEG）为第二表面活性剂的生物相容性磁流体。磁化强度的测量结果表明，电子辐照高达1000 Gy的情况下，仅用一种表面活性剂的第一个样品的饱和磁化强度降低50%，而在第二个生物相容性磁性流体的情况下，仅观察到25%的饱和磁化强度降低。在第一种磁性流体中，当磁性颗粒也被PEG覆盖时，辐射引起磁性颗粒比第二种情况下更高的沉降。结果表明，PEG具有保护作用.
英文摘要：
The radiation stability of biocompatibile magnetic fluid used in nanomedicine after electron irradiation was studied. Two types of the water-based magnetic fluids were prepared. The first one was based on the magnetite nanoparticles stabilized by one surfactant natrium oleate. The second one was biocompatibile magnetic fluid stabilized with two surfactants, natrium oleate as a first surfactant and Poly(ethylene glycol) (PEG) as a second surfactant. The magnetization measurements showed that electron irradiation up to 1000Gy caused 50% reduction of saturation magnetization in the case of the first sample with only one surfactant while in the case of the second biocompatibile magnetic fluid, only 25% reduction of saturation magnetization was observed. In the first magnetic fluid the radiation caused the higher sedimentation of the magnetic particles than in the second case, when magnetic particles are covered also with PEG. The obtained results show that PEG behave as a protective element.
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