二级催化准物种产生一级相变
Second-Order Catalytic Quasispecies Yields First-Order Phase Transition
摘要：
准种模型描述了与生命起源和病毒演化动力学相关的过程。我们讨论了不同反应级的催化复制如何影响反映从定域准种种群到离域准种种群转变的错误灾难。具体地说，我们发现，二阶机制导致一阶不连续相变的可行的人口分数，并得出结论，“高”的相互作用的“低”的过渡。我们讨论了理解高度变异RNA病毒复制的潜在影响。
英文摘要：
The quasispecies model describes processes related to the origin of life and viral evolutionary dynamics. We discuss how the error catastrophe that reflects the transition from localized to delocalized quasispecies population is affected by catalytic replication of different reaction orders. Specifically, we find that 2nd order mechanisms lead to 1st order discontinuous phase transitions in the viable population fraction, and conclude that the "higher" the interaction the "lower" the transition. We discuss potential implications for understanding the replication of highly mutating RNA viruses.
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