寿命正电子湮没谱与光灭活细菌
Lifetime positron annihilation spectroscopy and photo-inactivated bacteria
摘要：
结合正电子和可见光照射在光动力治疗（PDT）的应用进行了分析。PDT的目的和目标是在光照射期间通过注入靶细胞的光敏剂的光活化氧杀死或不可逆地氧化损伤病原细胞，或者更确切地说是它们的细胞壁、细胞膜、肽和核酸。本文以革兰氏阳性菌和革兰氏阴性菌为例，在简要综述文献的基础上，提出了在PDT过程中应用寿命正电子湮没谱技术控制光损伤细胞的论点。
英文摘要：
Combined positron and visible light irradiations in the photodynamical therapy (PDT) applications are analyzed. Objectives and goals of PDT are killing or irreversible oxidative damage of pathogenic cells, or rather their cell walls, cell membranes, peptides, and nucleic acids by photo-activated oxygen of photosentizer injected into the target cell during light irradiation. In this paper, the arguments for involving of lifetime positron annihilation spectroscopy to control of photodamaging cells in the course of the PDT procedure are given on the examples of gram-positive and gram-negative bacteria basing on a brief survey of the literature.
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