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arXiv 0910.5684physics.bio-phphysics.space-ph
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Geant4-DNA项目

The Geant4-DNA project

S. Incerti, G. Baldacchino, M. Bernal, R. Capra, C. Champion, Z. Francis, S. Guatelli, P. Gueye, A. Mantero, B. Mascialino, P. Moretto, P. Nieminen, A. Rosenfel… 展开作者

S. Incerti, G. Baldacchino, M. Bernal, R. Capra, C. Champion, Z. Francis, S. Guatelli, P. Gueye, A. Mantero, B. Mascialino, P. Moretto, P. Nieminen, A. Rosenfeld, C. Villagrasa, C. Zacharatou

备注：
presented by S. Incerti at the ASIA SIMULATION CONFERENCE 2009, October 7-9, 2009, Ritsumeikan University, Shiga, Japan
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摘要：

Geant 4-DNA项目提议开发一个基于通用Geant 4蒙特卡罗模拟工具包并完全包含其中的开源模拟软件。该软件的主要目的是在细胞和亚细胞尺度上模拟电离辐射引起的生物损伤。该项目最初是由欧洲航天局发起的，目的是预测未来长期空间探索任务中可能影响宇航员的辐射有害影响。在本文中，Geant 4-DNA合作概述了整个正在进行的项目，包括在最新的Geant 4公开版本（9.3 BETA）中已经提供的最新进展，以及模拟染色质纤维直接照射的示例。预期扩展涉及几个研究领域，如粒子物理学，化学和细胞和分子生物学，在一个完全interdiciplinary活动的Geant 4合作进行了讨论。

英文摘要：

The Geant4-DNA project proposes to develop an open-source simulation software based and fully included in the general-purpose Geant4 Monte Carlo simulation toolkit. The main objective of this software is to simulate biological damages induced by ionising radiation at the cellular and sub-cellular scale. This project was originally initiated by the European Space Agency for the prediction of deleterious effects of radiation that may affect astronauts during future long duration space exploration missions. In this paper, the Geant4-DNA collaboration presents an overview of the whole ongoing project, including its most recent developments already available in the last Geant4 public release (9.3 BETA), as well as an illustration example simulating the direct irradiation of a chromatin fibre. Expected extensions involving several research domains, such as particle physics, chemistry and cellular and molecular biology, within a fully interdiciplinary activity of the Geant4 collaboration are also discussed.

机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。

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